American scientists from the University of California at San Francisco for the first time created baby mice from the cells of two males. The findings of the study are described in an article published in the journal Nature.

First, the team isolated skin cells from the tails of male mice and turned them into induced pluripotent stem cells (iPSCs), reprogrammed, differentiated cells that take on the characteristics of embryonic stem cells, meaning they can develop into different types of cells or tissues.

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The researchers then treated them with a special drug that converted male mouse stem cells into female cells. The result was functional eggs that were artificially fertilized. The embryos were then implanted into female mice. About one percent of the embryos - 7 out of 630 - grew into live babies. The offspring was formed without pathologies and could subsequently become ordinary parents.

Whether it is possible to use the same technology for humans, scientists do not know, especially since the number of surviving cubs was small. Nevertheless, new knowledge can form the basis for reproductive biology and fertility research, as well as in the field of stem cell research. In the future, for example, it may be possible to reproduce endangered mammals from a single male.